Apomixis has been widely concerned because of its great potential in heterosis fixation. Artificial apomixis is an important direction of current apomixis research. Mitosis instead of Meiosis (MIME) produces diploid gametes that is identical with the maternal genetic composition and is a key step in the artificial creation of apomixes. This paper reviews the occurrence of MIME and its application in crop apomixis and the problems encountered, in an aim to provide reference for expanding the application of MIME in crop apomixis.
无融合生殖因其在杂种优势固定中的巨大潜力而受到广泛关注，人工创制无融合生殖是当前无融合生殖研究的重要方向，有丝分裂替代减数分裂 (Mitosis instead of Meiosis，MIME) 能产生与母本遗传组成完全一致的二倍体配子，是人工创制无融合生殖的关键步骤。文中对MIME 的发生及其在作物无融合生殖中的应用以及MIME 应用中的问题进行综述，以期为扩大MIME 在作物无融合生殖中的应用提供参考。.
Keywords: apomixis; crops; diploid gametes; heterosis; mitosis instead of meiosis.