Theranostic drug test incorporating the bone-marrow microenvironment can predict the clinical response of acute myeloid leukaemia to chemotherapy

Br J Haematol. 2020 Jun;189(6):e254-e258. doi: 10.1111/bjh.16684. Epub 2020 Apr 28.
No abstract available

Keywords: acute myeloid leukaemia; bone-marrow microenvironment; drug resistance; leukaemia stem cell; three-dimensional co-culture.

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antineoplastic Agents / pharmacology*
  • Bone Marrow* / metabolism
  • Bone Marrow* / pathology
  • Cell Line, Tumor
  • Coculture Techniques
  • Humans
  • Leukemia, Myeloid, Acute* / drug therapy
  • Leukemia, Myeloid, Acute* / metabolism
  • Leukemia, Myeloid, Acute* / pathology
  • Theranostic Nanomedicine*
  • Tumor Microenvironment / drug effects*

Substances

  • Antineoplastic Agents