Intralesional triamcinolone acetonide in notalgia paresthetica: Treatment outcomes in five patients

Dermatol Ther. 2020 Jul;33(4):e13462. doi: 10.1111/dth.13462. Epub 2020 May 8.

Abstract

Numerous treatment modalities have been tried with diverse results for pruritus due to notalgia paresthetica (NP). Corticosteroids suppress ectopic neural discharges from injured nerve fibers and also have short-lived suppressive effect on transmission in normal C-fibers. Herein, we evaluated the efficacy of intralesional triamcinolone acetonide in the treatment of NP. The medical reports of five patients who had been diagnosed with NP and treated with intralesional triamcinolone acetonide injections were retrospectively evaluated. Triamcinolone acetonide solution was injected intradermally (10 mg/mL; 0.1 mL/cm2 ) every 3 weeks for a maximum of four treatments. The severity of itch was scored by the patients on a combined numerical and visual analogue scale. After treatment, reduction in itch severity scores varied between 33% and 100%.

Keywords: corticosteroid; intralesional injection; itching; notalgia paresthetica; treatment.

MeSH terms

  • Humans
  • Injections, Intralesional
  • Peripheral Nervous System Diseases*
  • Pruritus / diagnosis
  • Pruritus / drug therapy
  • Retrospective Studies
  • Treatment Outcome
  • Triamcinolone Acetonide*

Substances

  • Triamcinolone Acetonide