Bacterial Imprinting Methods and Their Applications: An Overview

Crit Rev Anal Chem. 2021;51(7):609-618. doi: 10.1080/10408347.2020.1755822. Epub 2020 Apr 26.

Abstract

Microbial contaminations and infections are hazardous and pose crucial concerns for humans. They result in severe morbidity and mortality around the globe. Even though dish-culturing, polymerase chain reaction (PCR), an enzyme-linked immunosorbent assay (ELISA) exhibits accurate and reliable detection of bacteria but these methods are time-consuming, laborious, and expensive. This warrants early detection and quantification of bacteria for timely diagnosis and treatment. Bacteria imprinting ensures a solution for selective and early detection of bacteria by snagging them inside their imprinted cavities. This review provides an insight into MIPs based bacterial detection strategies, challenges, and future perspectives.

Keywords: Bacteria imprinting; applications; direct and indirect detection.

Publication types

  • Review

MeSH terms

  • Bacteria / genetics
  • Enzyme-Linked Immunosorbent Assay
  • Humans
  • Molecular Imprinting*