The Effects of Smoking on IgE, Oxidative Stress and Haemoglobin Concentration

Asian Pac J Cancer Prev. 2020 Apr 1;21(4):1069-1072. doi: 10.31557/APJCP.2020.21.4.1069.

Abstract

Background: Smoking is a well-known related factor for many health problems in a human being through different ways of exposure.

Objectives: Thie aim of the study was to examine the effects of different types of cigarette smoking on hemoglobin level, high sensitive C-Reactive Protein (hsCRP), Malondialdehyde (MDA), and IgE levels in healthy adult subjects.

Methods: One hundred seventy-one healthy adult females and males were included in this study. They divided into four groups: cigarette, shisha, passive smokers, and non-smokers groups. Serum samples from all groups analyzed for hemoglobin, hsCRP, IgE, and malondialdehyde level.

Results: The mean MDA, IgE, and hemoglobin levels significantly increased in both smokers (cigarette and Shisha groups) and passive smokers than in non-smokers group (p<0.05). The hsCRP levels were significantly increased (p<0.05) in cigarette and Shisha smokers compared to non-smokers. At the same time, there was a non-significant relationship between passive smoker in comparison to non-smokers (p>0.05).

Conclusion: This study concluded that smoking, including cigarette and shisha, even passive smoking harmed health through increasing Malondialdehyde, serum IgE and hs-CRP levels in the body.

Keywords: IgE; Malondialdehyde; smoking.

MeSH terms

  • Adult
  • Case-Control Studies
  • Female
  • Follow-Up Studies
  • Hemoglobins / analysis*
  • Humans
  • Immunoglobulin E / blood*
  • Iraq / epidemiology
  • Male
  • Middle Aged
  • Oxidative Stress / drug effects*
  • Prognosis
  • Smoking / adverse effects*
  • Smoking / blood*
  • Smoking / epidemiology
  • Young Adult

Substances

  • Hemoglobins
  • Immunoglobulin E