A Novel Cryo-EM Structure Enables Development of Selective Cannabinoid Receptor Drugs

Biochemistry. 2020 May 5;59(17):1643-1644. doi: 10.1021/acs.biochem.0c00263. Epub 2020 Apr 23.

Authors

Gregory Zilberg¹, Daniel Wacker²

Affiliations

¹ Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, New York 10029, United States.
² Department of Pharmacological Sciences and Neuroscience, Icahn School of Medicine at Mount Sinai, New York, New York 10029, United States.

PMID: 32324378
DOI: 10.1021/acs.biochem.0c00263

No abstract available

Publication types

Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

MeSH terms

Cryoelectron Microscopy*
Drug Discovery*
Models, Molecular
Protein Conformation
Receptors, Cannabinoid / chemistry
Receptors, Cannabinoid / metabolism*

Substances

Receptors, Cannabinoid

Grants and funding

R35 GM133504/GM/NIGMS NIH HHS/United States