Evaluation and comparison of the effect of honey, milk and combination of honey-milk on experimental induced second-degree burns of Rabit

Seyed Mehdi Hosseini; Reza Fekrazad; Hamid Malekzadeh; Parviz Farzadinia; Mohammadreza Hajiani

doi:10.4103/jfmpc.jfmpc_801_19

Evaluation and comparison of the effect of honey, milk and combination of honey-milk on experimental induced second-degree burns of Rabit

J Family Med Prim Care. 2020 Feb 28;9(2):915-920. doi: 10.4103/jfmpc.jfmpc_801_19. eCollection 2020 Feb.

Authors

Seyed Mehdi Hosseini¹, Reza Fekrazad², Hamid Malekzadeh¹, Parviz Farzadinia³, Mohammadreza Hajiani³

Affiliations

¹ Department of Oral and Maxillofacial Surgery, Dental School, AJA University of Medical Science, Bushehr, Iran.
² Department of Periodontology, Dental School, AJA University of Medical Science, Bushehr, Iran.
³ Department of Biology and Anatomical Science, Faculty of Medicine, Bushehr University of Medical Science, Bushehr, Iran.

Abstract

Introduction: Burn can happen in any area and causes dominant changes in the quality of normal tissues. The aim of present article is evaluation and comparison the effect of milk, natural honey, and combination of honey-milk on healing of burnt wound.

Method and material: A 4-week trial study was carried out on 10 Albino New Zealand rabbits. All dry burned wound was created on the back of the scapula by a 1 * 1 cm metal block. First group received honey dressing, second group milk dressing, third group honey-milk dressing, and the fourth group 5% sulfadiazine dressing. Sampling was performed at days 1, 10, and 20. Measurement of wound size was done in days 1, 7, 14, 21, 28. The obtained data and information were analyzed by two-way ANOVA and Duncan tests using SPSS.

Results: Result show that combination of milk-honey dressing had most significant effect on the improvement of wound healing in the recipient rabbits after a 4-week study. The size of burn wound in four different group was: Honey milk combination 0.428 cm², honey 0.547 cm², milk 0.579 cm² and sulfadiazine 0.873 cm².

Conclusion: All dressing can accelerate wound healing and have promotive effect on wound healing but the combination of honey-milk had the greatest effect. Honey, milk, and sulfadiazine had next grade of effectiveness.

Keywords: Honey; milk; wound dressing; wound healing.