Background: Controversy exists regarding the need for antimicrobial prophylaxis prior to dental procedures following spinal fusion. In this review, we attempt to synthesize a comprehensive summary of the published literature to provide recommendations on the use of antimicrobial prophylaxis before dental procedures in patients with a history of spinal fusion.
Methods: We searched PubMed, Web of Science, Cochrane Library, and EMBASE databases from inception to February 2018. Eligible studies included patients with a history of spinal fusion treated with or without antimicrobial prophylaxis in preparation for dental procedures. Two reviewers independently assessed the eligibility of potential studies and extracted data. Outcomes of interest were the indications and efficacy of antimicrobial prophylaxis to protect against infection of spinal prostheses with dental origin.
Results: A total of 1,909 articles were initially screened. After inclusion and exclusion criteria were applied, one study was found specifically relating to dental prophylaxis and spine surgery. The survey, as well as objective studies and professional organization guidelines on dental prophylaxis in patients with total hip and knee replacements, were reviewed to add context to the controversy.
Conclusions: There is a significant paucity of literature regarding dental prophylaxis in spine surgery patients. Although there has been a recent movement away from recommending antimicrobial prophylaxis before dental work in patients with other forms of orthopaedic prostheses, the gap in the literature addressing spine patients represents an important question that requires more targeted and specific research.
Keywords: Dental prophylaxis; infection; spinal fusion; spine surgery.
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