Three new acylphloroglucinol glucosides from the roots of Lysidice rhodostegia and their antioxidant activities

Carbohydr Res. 2020 Jun:492:108012. doi: 10.1016/j.carres.2020.108012. Epub 2020 Apr 14.

Abstract

Three new acylphloroglucinol glucosides, rhodosides A-C (1-3), and three known ones (4-6) were isolated from the roots of Lysidice rhodostegia. The new structures were identified by MS, NMR, and acid hydrolysis. In addition, the antioxidant capacities of the isolated compounds were evaluated using DPPH radical-scavenging assay, and compounds 1-6 exhibited obvious antioxidant activities with IC50 values of 24.65 ± 1.27 to 38.11 ± 1.35 μM.

Keywords: Acylphloroglucinol glucoside; Antioxidant activity; Lysidice rhodostegia.

MeSH terms

  • Antioxidants / chemistry
  • Antioxidants / isolation & purification
  • Antioxidants / pharmacology*
  • Biphenyl Compounds / antagonists & inhibitors*
  • Carbohydrate Conformation
  • Fabaceae / chemistry*
  • Glucosides / chemistry
  • Glucosides / isolation & purification
  • Glucosides / pharmacology*
  • Phloroglucinol / chemistry
  • Phloroglucinol / isolation & purification
  • Phloroglucinol / pharmacology*
  • Picrates / antagonists & inhibitors*
  • Plant Extracts / chemistry
  • Plant Extracts / isolation & purification
  • Plant Extracts / pharmacology*
  • Plant Roots / chemistry*

Substances

  • Antioxidants
  • Biphenyl Compounds
  • Glucosides
  • Picrates
  • Plant Extracts
  • 1,1-diphenyl-2-picrylhydrazyl
  • Phloroglucinol