Perianal fistula and the ileoanal pouch - different aetiologies require distinct evaluation

Colorectal Dis. 2020 Oct;22(10):1436-1439. doi: 10.1111/codi.15074. Epub 2020 May 14.

Abstract

Aim: Restorative proctocolectomy has been widely adopted as the procedure of choice for restoring gastrointestinal continuity following proctocolectomy. It is often associated with improved quality of life and high patient satisfaction; however, the development of a pouch anal fistula can cause significant morbidity. Pouch fistulas are notoriously difficult to treat and there is great heterogeneity in the management reported of these fistulas. A lack of classification, and the assumption that fistulas originating from completely different aetiologies will behave and respond similarly to a particular treatment strategy, precludes meaningful comparison of management outcomes. We aim to introduce consistency in the reporting of pouch fistulas using a novel classification system.

Methods: A consensus process involving clinicians experienced in the management of pouch fistulas from two high volume tertiary centres was performed.

Results: We propose that pouch anal fistulas should be classified into four distinct groups according to their aetiology: group 1, anastomotic related; group 2, inflammatory bowel disease related, with sub-classifications Crohn's (type A) and non-Crohn's (type B) in origin; group 3, cryptoglandular related; and group 4, malignancy related.

Conclusion: Classification of pouch fistulas according to their aetiology will provide consistency in the literature and improve the quality of prospective evidence for the management of pouch fistulas.

Keywords: Crohn's disease; Ileal pouch anal anastomosis; classification; pouch anal fistula; pouch fistula; pouch vaginal fistula.

MeSH terms

  • Colonic Pouches* / adverse effects
  • Humans
  • Proctocolectomy, Restorative* / adverse effects
  • Prospective Studies
  • Quality of Life
  • Rectal Fistula* / etiology
  • Rectal Fistula* / surgery