The Effect of Complexity of the Surgical Field on Perioperative Outcomes of Robot-Assisted Radical Cystectomy

Urology. 2020 Jul:141:95-100. doi: 10.1016/j.urology.2020.03.033. Epub 2020 Apr 14.

Abstract

Objective: To report the outcomes of patients who underwent robot-assisted radical cystectomy (RARC) and have a history of previous pelvic surgery and/or radiation.

Methods: Retrospective review of our prospectively maintained database between 2005 and 2018. Patients were divided into 3 groups based on surgical complexity; Complexity grade 1 included patients who did not have any history of prior pelvic surgery or radiation (n = 323); Complexity grade 2 included those who had history of a single pelvic surgery or radiation (n = 186); and Complexity grade 3 included those who had history of 2 or more pelvic surgeries, or one or more pelvic surgery and radiation (n = 80). All groups were compared in terms of perioperative outcomes. Multivariate linear and logistic regression models were used to depict the predictors of operative time, ≥500 ml blood loss, 90-day complications, high grade complications, and readmissions.

Results: Complexity grades 2 and 3 exhibited higher 90-day complications compared to CG1 (CG3: 74%, CG1: 59%, CG2: 68%, P = .02), and high grade complications (CG3: 24%, CG1: 13%, CG2 18%, P = .03). On multivariate linear and logistic regression models, CG 3 was significantly associated with higher 90-day complications (OR 2.18, 95% CI 1.21-3.94, P <.01) but not significantly associated with higher rates of significant blood loss, longer operative time, 90-day high grade complications and readmissions.

Conclusion: Patients with higher complexity of the surgical field exhibited more complications after robot-assisted radical cystectomy, but not readmissions.

MeSH terms

  • Aged
  • Blood Loss, Surgical* / prevention & control
  • Blood Loss, Surgical* / statistics & numerical data
  • Cystectomy* / adverse effects
  • Cystectomy* / instrumentation
  • Cystectomy* / methods
  • Cystectomy* / statistics & numerical data
  • Female
  • Humans
  • Lymph Node Excision / methods*
  • Male
  • Neoplasm Invasiveness
  • Neoplasm Staging
  • Operative Time
  • Patient Readmission / statistics & numerical data
  • Pelvis / radiation effects
  • Pelvis / surgery*
  • Postoperative Complications* / diagnosis
  • Postoperative Complications* / etiology
  • Postoperative Complications* / mortality
  • Retrospective Studies
  • Robotic Surgical Procedures / adverse effects
  • Robotic Surgical Procedures / methods
  • United States / epidemiology
  • Urinary Bladder Neoplasms* / epidemiology
  • Urinary Bladder Neoplasms* / pathology
  • Urinary Bladder Neoplasms* / surgery