Treatment of a case presenting as critical adenoviral ARDS using Cidofovir with early combinatorial prone ventilation and ECMO

Chao Liu; Wei-Wei Ning; Yan-Bin Chen; Ye-Han Zhu; Yu Xia; Jian-An Huang; Cheng Chen

doi:10.1111/crj.13196

Treatment of a case presenting as critical adenoviral ARDS using Cidofovir with early combinatorial prone ventilation and ECMO

Clin Respir J. 2020 Aug;14(8):780-788. doi: 10.1111/crj.13196. Epub 2020 May 5.

Authors

Chao Liu¹, Wei-Wei Ning¹, Yan-Bin Chen¹, Ye-Han Zhu¹, Yu Xia², Jian-An Huang¹, Cheng Chen¹

Affiliations

¹ Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Soochow University, Suzhou, China.
² Department of Microbiology, Suzhou Center for Disease Control and Prevention, Suzhou, China.

Abstract

Here, we report a case of adenoviral pneumonia associated with critical ARDS treated with Cidofovir, prone ventilation and extracorporeal membrane oxygenation (ECMO). The patient responded well to therapy and recovered without further complications. Cidofovir, with early prone ventilation and ECMO support, may be a therapeutic option for patients with critical ARDS related to adenoviral pneumonia.

Keywords: ARDS; Cidofovir; ECMO; adenovirus pneumonia; prone ventilation.

Grants and funding

First Affiliated Hospital of Soochow University