Clinical Progression of COVID-19 Patient with Extended Incubation Period, Delayed RT-PCR Time-to-positivity, and Potential Role of Chest CT-scan

Acta Med Indones. 2020 Jan;52(1):80-83.

Abstract

Coronavirus Disease 2019 (COVID-19), previously called 2019-nCoV, is a novel disease caused by SARS- CoV-2 which was first identified as outbreak of unknown respiratory illness in Wuhan, China. COVID- 19 was declared as global health emergency by WHO on March 11, 2020 and quickly elevated to global pandemic on 11 March 2020. COVID-19 symptom is highly various in each patient, with fever, fatigue, shortness of breath, and cough as the main presenting symptoms. Patient with COVID-19 may shows severe symptom with severe pneumonia and ARDS, mild symptom resembling simple upper respiration tract infection, or even completely asymptomatic. Approximately 80% of cases is mild. However the number may changes as more people are getting tested. Some experts are estimating that up to 50% of all cases may be asymptomatic carrier.

Keywords: COVID-19, SARS, COV-2-.

MeSH terms

  • Betacoronavirus* / genetics
  • COVID-19
  • COVID-19 Testing
  • Clinical Laboratory Techniques
  • Coronavirus Infections / diagnosis*
  • Humans
  • Infectious Disease Incubation Period*
  • Pandemics
  • Pneumonia, Viral / diagnosis*
  • Reverse Transcriptase Polymerase Chain Reaction
  • SARS-CoV-2
  • Time Factors
  • Tomography, X-Ray Computed