The daily computed weighted averaging basic reproduction number R 0 , k , ω n for MERS-CoV in South Korea

Physica A. 2016 Jun 1:451:190-197. doi: 10.1016/j.physa.2016.01.072. Epub 2016 Feb 2.

Abstract

In this paper, we propose the daily computed weighted averaging basic reproduction number R 0 , k , ω n for Middle East respiratory syndrome coronavirus (MERS-CoV) outbreak in South Korea, May to July 2015. We use an SIR model with piecewise constant parameters β (contact rate) and γ (removed rate). We use the explicit Euler's method for the solution of the SIR model and a nonlinear least-square fitting procedure for finding the best parameters. In R 0 , k , ω n , the parameters n , k , and w denote days from a reference date, the number of days in averaging, and a weighting factor, respectively. We perform a series of numerical experiments and compare the results with the real-world data. In particular, using the predicted reproduction number based on the previous two consecutive reproduction numbers, we can predict the future behavior of the reproduction number.

Keywords: Explicit Euler’s method; MERS-CoV; Optimal parameter fitting; SIR model.