Background: As deep brain stimulation (DBS) and radiation therapy (RT) have become established treatments for movement disorders and malignancies respectively, patients being treated with both simultaneously are becoming more frequent.
Objectives: Literature regarding the safety of RT in patients with implanted DBS is scarce, and there are no clear guidelines on how to manage them.
Methods: We present a follow-up of two Parkinson's Disease (PD) patients with DBS undergoing RT in the context of previous literature.
Results: No adverse events nor malfunctioning of the DBS system were observed. This was in line with previous reports.
Conclusions: Since there are no clear safety guidelines for RT in DBS patients, it is important to document experience in this field. A combined approach involving multidisciplinary discussions between neurosurgeons, radiotherapists, clinical oncologists and neurologists is recommended.
Keywords: Parkinson’s Disease; deep brain stimulation; radiation therapy; safety guidelines.