Disseminated Mucormycosis Due to Saksenaea vasiformis Complex in an Immunocompetent Adult with Sustained Response to Posaconazole Treatment

Mycopathologia. 2020 Jun;185(3):577-581. doi: 10.1007/s11046-020-00443-y. Epub 2020 Apr 11.

Abstract

Saksenaea vasiformis complex is an emerging cause of mucormycosis. We report a case of an immunocompetent patient presenting with a non-resolving lung mass who developed multiple skin nodules. Skin biopsy yielded Saksenaea vasiformis complex. This showcases an uncommon occurrence of disseminated Saksenaea infection without cutaneous inoculation that improved with posaconazole.

Keywords: Immunocompetent; Mucormycosis; Posaconazole.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Antifungal Agents / therapeutic use*
  • Asian People
  • Back
  • Follow-Up Studies
  • Forehead
  • Humans
  • Immunocompetence
  • Male
  • Mucormycosis / diagnostic imaging
  • Mucormycosis / drug therapy*
  • Positron Emission Tomography Computed Tomography
  • Singapore
  • Skin / microbiology
  • Skin / pathology
  • Thorax
  • Tomography, X-Ray Computed
  • Triazoles / therapeutic use*

Substances

  • Antifungal Agents
  • Triazoles
  • posaconazole

Supplementary concepts

  • Saksenaea infection