Brain Malformations at All Ages: From Aunt Minnie to Zebras for General Radiologists

Jungwhan John Choi; Bindu N Setty; Edward Y Lee

doi:10.1016/j.rcl.2019.12.002

Brain Malformations at All Ages: From Aunt Minnie to Zebras for General Radiologists

Radiol Clin North Am. 2020 May;58(3):463-474. doi: 10.1016/j.rcl.2019.12.002. Epub 2020 Feb 20.

Authors

Jungwhan John Choi¹, Bindu N Setty², Edward Y Lee³

Affiliations

¹ Department of Radiology, Boston Children's Hospital, Harvard Medical School, 300 Longwood Avenue, Main Building, 2nd Floor, Boston, MA 02115, USA.
² Department of Radiology, Boston Medical Center, FGH Building, 3rd Floor, Boston, MA 02118, USA.
³ Department of Radiology, Boston Children's Hospital, Harvard Medical School, 300 Longwood Avenue, Main Building, 2nd Floor, Boston, MA 02115, USA. Electronic address: Edward.lee@childrens.harvard.edu.

PMID: 32276697
DOI: 10.1016/j.rcl.2019.12.002

Abstract

Congenital brain malformations comprise a spectrum of disorders that result from a variety of causes, including genetic abnormalities, ischemia, infections, and toxic exposures. Although most cases are discovered in infancy or childhood, clinically occult abnormalities may prove to be confounding, especially if first encountered later in life on imaging examinations obtained for other indications or in the context of superimposed pathology. This review article provides an overview of congenital brain malformations because they may be encountered at all ages for general radiologists.

Keywords: Congenital brain; Congenital brain malformations; Pediatric brain.

Publication types

Review

MeSH terms

Adult
Brain / abnormalities*
Brain / diagnostic imaging*
Diagnostic Imaging / methods*
Humans
Infant