Is the risk of lymphedema life-long following treatment for gynecologic cancer?-A case report

Curr Probl Cancer. 2020 Aug;44(4):100538. doi: 10.1016/j.currproblcancer.2020.100538. Epub 2020 Jan 16.

Abstract

Lymphedema is a common complication following oncologic surgeries and is classically described to occur months to a few years after these procedures. A 64 year-old woman with history of total abdominal hysterectomy and bilateral salpingo-oophorectomy developed right-sided lower extremity lymphedema 7 years after the surgeries. Lymphographic imaging performed approximately twenty years after the original surgeries revealed development of subclinical, asymptomatic lymphedema on the contralateral lower extremity. This delayed presentation of lymphedema after initial injury, is the first described case of subclinical lymphedema without detectable lymphatic injury, making it important to continuously monitor patients at risk for lymphedema long-term.

Keywords: Gynecologic cancer; Hysterectomy; Indocyanine green lymphography; Lower extremity lymphedema; Salpingo-oophorectomy; Subclinical lymphedema.

Publication types

  • Case Reports

MeSH terms

  • Anastomosis, Surgical
  • Female
  • Humans
  • Hysterectomy / adverse effects*
  • Lower Extremity / pathology*
  • Lymph Node Excision / adverse effects*
  • Lymphedema / etiology*
  • Lymphedema / pathology
  • Lymphedema / surgery
  • Middle Aged
  • Salpingo-oophorectomy / adverse effects*
  • Time Factors
  • Uterine Cervical Neoplasms / pathology
  • Uterine Cervical Neoplasms / surgery*