Arresting the time-dependent H2O2 mediated synthesis of gold nanoparticles for analytical detection and preparative chemistry

Pierangelo Gobbo; Mia J Biondi; Jordan J Feld; Mark S Workentin

doi:10.1039/c3tb20913j

Arresting the time-dependent H₂O₂ mediated synthesis of gold nanoparticles for analytical detection and preparative chemistry

J Mater Chem B. 2013 Sep 7;1(33):4048-4051. doi: 10.1039/c3tb20913j. Epub 2013 Jul 24.

Authors

Pierangelo Gobbo¹, Mia J Biondi, Jordan J Feld, Mark S Workentin

Affiliation

¹ The University of Western Ontario and the Centre for Materials and Biomaterials Research, Richmond Street, London, Ontario, Canada. mworkent@uwo.ca.

PMID: 32260956
DOI: 10.1039/c3tb20913j

Abstract

The time-dependent progression from gold nanosponges (AuNS) to discrete small gold nanoparticles (AuNPs) mediated by H₂O₂ in MES buffer is blocked by the addition of a thiol, glutathione. This represents an important improvement for the plasmonic ELISA, and also leads to a time-dependent approach for the synthesis of AuNS and AuNPs in water with precise control over nanostructure size.