Peripheral trigeminal branch stimulation for refractory facial pain: A single-center experience

Clin Neurol Neurosurg. 2020 Jul:194:105819. doi: 10.1016/j.clineuro.2020.105819. Epub 2020 Apr 1.

Abstract

Objective: Facial pain refractory to medical treatments may benefit from neurosurgical interventions. Only a few studies have reported on the efficacy of peripheral trigeminal stimulation and more specifically supraorbital nerve (SON) and infraorbital nerve (ION) stimulation for the treatment of facial pain.

Patients and methods: In the present study, we identified all patients at our institution who underwent SON and/or ION stimulation for treatment of facial pain due to post-herpetic, traumatic or idiopathic etiology. Relevant pre and post-operative outcomes were analyzed.

Results: We identified 15 patients who underwent SON and/or ION stimulation. Among them, 12 (80 %) endorsed >50 % pain relief during the trial stimulation period. After a median follow-up of 5.8 months with permanent implantation, 1 patient (8.3 %) was diagnosed with lead erosion and IPG migration, two patients had lead infections (16.7 %) and one (8.3 %) had wound dehiscence. No lead migrations were identified during the long-term follow-up. The VAS score showed a statistically significant reduction from a median pre-operative score of 7 to a post-operative score of 1.8 (p = 0.011), which corresponded to a 74.3 % average pain reduction.

Conclusion: SON and/or ION stimulation can be an effective treatment for intractable facial pain due to post-herpetic, traumatic or idiopathic etiology; however the complication rate is relatively high. Future prospective studies with longer follow-up periods are warranted.

Keywords: Facial pain; Infraorbital nerve; Neuropathic pain; Stimulation; Supraorbital nerve; Trigeminal neuralgia.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Electric Stimulation Therapy / adverse effects
  • Electric Stimulation Therapy / methods*
  • Electrodes, Implanted / adverse effects
  • Facial Nerve Injuries / complications
  • Facial Nerve Injuries / therapy
  • Facial Pain / surgery*
  • Facial Pain / therapy*
  • Female
  • Follow-Up Studies
  • Foreign-Body Migration / epidemiology
  • Humans
  • Male
  • Middle Aged
  • Neuralgia, Postherpetic / therapy
  • Neurosurgical Procedures / methods
  • Pain Measurement
  • Pain, Intractable
  • Peripheral Nerves
  • Postoperative Complications / epidemiology
  • Retrospective Studies
  • Treatment Outcome
  • Trigeminal Nerve*