ESCRTing Heterochromatin Out of the Nuclear Periphery

Matías Capella; Sigurd Braun

doi:10.1016/j.devcel.2020.03.013

ESCRTing Heterochromatin Out of the Nuclear Periphery

Dev Cell. 2020 Apr 6;53(1):3-5. doi: 10.1016/j.devcel.2020.03.013.

Authors

Matías Capella¹, Sigurd Braun²

Affiliations

¹ Department of Physiological Chemistry, Biomedical Center, Ludwig-Maximilians-Universität München, Planegg-Martinsried, Germany.
² Department of Physiological Chemistry, Biomedical Center, Ludwig-Maximilians-Universität München, Planegg-Martinsried, Germany. Electronic address: sigurd.braun@bmc.med.lmu.de.

PMID: 32259492
DOI: 10.1016/j.devcel.2020.03.013

Abstract

ESCRT proteins fulfill an important function in membrane remodeling and scission. In this issue of Developmental Cell, Pieper et al. reveal that the ESCRT machinery releases the inner nuclear membrane protein Lem2 from heterochromatin, thus ensuring its function in nuclear envelope resealing after mitosis.

Publication types

Comment

MeSH terms

Endosomal Sorting Complexes Required for Transport
Heterochromatin*
Membrane Proteins
Mitosis
Nuclear Envelope*

Substances

Endosomal Sorting Complexes Required for Transport
Heterochromatin
Membrane Proteins