A Case of Drug-induced Linear IgA Bullous Dermatosis

Sofanit A Dessie; Davinder Singh; Varun Dobariya; Derek Evans; Peimei He

doi:10.7759/cureus.7175

A Case of Drug-induced Linear IgA Bullous Dermatosis

Cureus. 2020 Mar 4;12(3):e7175. doi: 10.7759/cureus.7175.

Authors

Sofanit A Dessie¹, Davinder Singh¹, Varun Dobariya¹, Derek Evans², Peimei He³

Affiliations

¹ Internal Medicine, Marshall University, Joan C. Edwards School of Medicine, Huntington, USA.
² Medicine, Cabell Huntington Hospital, Huntington, USA.
³ Internal Medicine, Marshall University, Huntington, USA.

Abstract

Linear immunoglobulin A (IgA) bullous dermatosis (LABD) presents as a rare autoimmune disease that can either occur spontaneously or induced by certain drugs, the most common of which is vancomycin. LABD is a subepidermal blistering disease that is diagnosed by detecting linear IgA bands along the basement membrane. We present a case of a 59-year-old man with worsening blistering skin rash who was treated with vancomycin and piperacillin-tazobactam for pneumonia.

Keywords: linear iga bullous dermatosis; piperacillin-tazobactam; vancomycin.

Publication types

Case Reports