[The immune system of adipose tissue: obesity-associated inflammation]

Pathologe. 2020 May;41(3):224-229. doi: 10.1007/s00292-020-00782-z.
[Article in German]

Abstract

Adipose tissue is an important endocrine organ. Via its secretion products, it cross-talks with other organs of the body and communicates the filling state of its triglyceride stores. Obesity is characterized by the excessive accumulation of body fat and leads to the infiltration and accumulation of immune cells in white adipose tissue. In this review article we introduce the various immune cell populations of adipose tissue and discuss their local and systemic influence.

Keywords: Adipokine; Brown adipose tissue; Macrophages; Overweight; White adipose tissue.

Publication types

  • Review

MeSH terms

  • Adipose Tissue / immunology*
  • Humans
  • Immune System
  • Inflammation / etiology
  • Inflammation / immunology*
  • Obesity / complications
  • Obesity / immunology*