Preliminary Clinical Data and the Comparison of the Safety and Efficacy of Autogenous Bone Grafts Versus Xenograft Implantations in Vertical Bone Deficiencies Before Dental Implant Installation

Transplant Proc. 2020 Sep;52(7):2248-2251. doi: 10.1016/j.transproceed.2020.02.099. Epub 2020 Apr 3.

Abstract

Two different techniques of vertical bone augmentation were compared to apply them to immunocompromised patients. One of them used autogenous bone graft; the other used xenograft. Thirty patients were involved in the study. Fifteen received autogenous ring shape grafts harvested from the mental region, and 15 received xenograft vertical tunnel augmentation. They have a total of 60 implants placed in the posterior region of the mandible (2 for each patient). Fixed full ceramic crowns were delivered. Two-year follow-up appointments after implant placement were made. Both autogenous bone grafts and xenografts showed similar long-term clinical regeneration outcome of vertical bone defects. Using autogenous bone rings simultaneously fixed by dental implants, the total treatment time and cost were shortened, but the traumatic reactions and complication rates were higher when compared to xenograft vertical tunnel augmentation. Due to the less traumatic character of the procedure, smaller complication rates and higher safety for the patients receiving chronic immunosuppression should avoid bone block augmentation and reap the benefits from vertical tunnel bone augmentation using xenograft materials.

Publication types

  • Clinical Trial
  • Comparative Study

MeSH terms

  • Adult
  • Alveolar Ridge Augmentation / adverse effects
  • Alveolar Ridge Augmentation / methods*
  • Animals
  • Bone Transplantation / adverse effects
  • Bone Transplantation / methods*
  • Dental Implants
  • Female
  • Heterografts
  • Humans
  • Immunocompromised Host*
  • Male
  • Mandible / surgery
  • Mandibular Reconstruction / methods
  • Middle Aged
  • Transplant Recipients*
  • Transplantation, Heterologous / adverse effects
  • Transplantation, Heterologous / methods*
  • Treatment Outcome

Substances

  • Dental Implants