New Approach to Treatment of High-Risk Allograft Recipients Under Chronic Immunosuppression With Tooth Loss. Evaluation of Safety and Longevity of Dental Implants: A Case Report

Transplant Proc. 2020 Oct;52(8):2558-2562. doi: 10.1016/j.transproceed.2020.02.103. Epub 2020 Apr 2.

Abstract

Patients eligible for solid organ transplant often lose their teeth and show numerous caries as well as periodontal and mucous membrane pathologies. The conventional methods of restoring teeth, including bridges and removable dentures, may result in progress of periodontal disease or even the creation of local source of general infection. Dental implants are not recognized as a therapeutic method in solid organ transplant recipients receiving immunosuppression because of the possibility of implant osseointegration disorders and suspicion as to the possibility of dysfunction of the transplanted organ and the spread of systemic infection. The authors present a case of the patient after liver transplant receiving immunosuppression treatment, who benefits from dental implants because of tooth loss. Three dental implants introduced because of the conventional loading protocol were healed and have osseointegrated without complication. Dental crown supported on them have restored the dental arches of the patient with good esthetic and functional effect. The results of treatment were stable in the 2-year follow-up period. No local signs of infection or general health disturbance were found. The function of the transplanted liver was unaffected.

Publication types

  • Case Reports

MeSH terms

  • Dental Implants*
  • Follow-Up Studies
  • Humans
  • Immunosuppression Therapy / adverse effects
  • Liver Transplantation / adverse effects*
  • Male
  • Middle Aged
  • Osseointegration
  • Periodontal Diseases / etiology
  • Periodontal Diseases / therapy*
  • Postoperative Complications / etiology
  • Postoperative Complications / therapy*
  • Tooth Loss / etiology
  • Tooth Loss / therapy*
  • Treatment Outcome

Substances

  • Dental Implants