Current update in domino liver transplantation

Int J Surg. 2020 Oct:82S:163-168. doi: 10.1016/j.ijsu.2020.03.017. Epub 2020 Mar 31.

Abstract

Orthotopic liver transplantation is an established treatment for end stage liver diseases as well as for some severe metabolic disorders. With increasing number of patients on the waiting list and the ongoing shortage of livers available, domino liver transplantation (DLT) became an option to further expand the organ donor pool. DLT utilizes the explanted liver of one liver transplant recipient as a donor graft in another patient. Despite being a surgically, and logistically demanding procedure, excellent results could be achieved in experienced high-volume transplant centers. In this review we present the current world status of DLT.

Keywords: Domino liver transplantation; Familial amyloidotic polyneuropathy; Maple syrup urine disease.

Publication types

  • Editorial
  • Review

MeSH terms

  • Amyloid Neuropathies, Familial / etiology
  • End Stage Liver Disease / surgery*
  • Humans
  • Liver / surgery*
  • Liver Transplantation / adverse effects
  • Liver Transplantation / methods*
  • Liver Transplantation / trends
  • Living Donors*
  • Patient Selection
  • Registries
  • Transplant Recipients*
  • Transplants / surgery*
  • Waiting Lists