Substituting Angiotensin-(1-7) to Prevent Lung Damage in SARS-CoV-2 Infection?

Circulation. 2020 May 26;141(21):1665-1666. doi: 10.1161/CIRCULATIONAHA.120.047297. Epub 2020 Apr 3.

Authors

Concepción Peiró^{1

2}, Salvador Moncada³

Affiliations

¹ Department of Pharmacology, School of Medicine, Universidad Autónoma de Madrid, Spain (C.P.).
² Instituto de Investigaciones Sanitarias IdiPAZ, Madrid, Spain (C.P.).
³ Manchester Cancer Research Centre, The University of Manchester, United Kingdom (S.M.).

No abstract available

Keywords: angiotensin receptor blockers; angiotensins; ards, human; lung inflammation; sars coronavirus; treatment; vascular endothelial cells.

MeSH terms

Angiotensin I / physiology*
Angiotensin-Converting Enzyme 2
Betacoronavirus*
COVID-19
Coronavirus Infections / prevention & control*
Humans
Lung / virology
Lung Injury / prevention & control*
Pandemics / prevention & control*
Peptide Fragments / physiology*
Peptidyl-Dipeptidase A / physiology
Pneumonia, Viral / prevention & control*
SARS-CoV-2

Substances

Peptide Fragments
Angiotensin I
Peptidyl-Dipeptidase A
ACE2 protein, human
Angiotensin-Converting Enzyme 2
angiotensin I (1-7)