A new diterpene and other compounds from the unripe female cones of Wollemia nobilis

Nat Prod Res. 2021 Nov;35(21):3839-3849. doi: 10.1080/14786419.2020.1741585. Epub 2020 Mar 31.

Abstract

In this work, the first phytochemical analysis ever performed on the unripe female cones of Wollemia nobilis W. G. Jones, K. D. Hill & J. M. Allen was described. The analysis evidenced the presence of a new derivative of sandaracopimaric acid together with rare diterpenoid derivatives and known compounds of chemosystematic and bioactivity relevance. Some of these were evidenced in the species or in the family for the first time during this study. The further implications of the isolated compounds in the field of chemosystematics, pharmacology and nutraceutics were discussed.

Keywords: 2α-hydroxy-8(14),15-sandaracopimaradien-18-oic acid; K. D. Hill & J. M. Allen; Wollemia nobilis W. G. Jones; chemotaxonomy; pharmacology; phytochemical analysis; unripe female cones.

MeSH terms

  • Diterpenes*
  • Phytochemicals
  • Tracheophyta*

Substances

  • Diterpenes
  • Phytochemicals