Fatal case of bacteremia caused by Streptococcus suis in a splenectomized man and a review of the European literature

Acta Microbiol Immunol Hung. 2020 Mar 30;67(3):148-155. doi: 10.1556/030.2020.01123. Print 2020 Oct 21.

Abstract

Streptococcus suis is an emerging zoonotic human pathogen, which is a causative agent of invasive infections in people who are in close contact with infected pigs or contaminated pork products. It is associated with severe systemic infections, most commonly meningitis and sepsis, which may lead to high rates of morbidity and mortality. Serotype 2 is the most prevalent type in S. suis infections in humans. We have reported a case of a very rapidly proceeding fatal human S. suis infection in a splenectomized, but otherwise immunocompetent patient in Hungary. We would like to highlight the attention for this pathogen for the risk group patients, not only pig breeders, veterinarians, abattoir workers, meat processing and transport workers, butchers and cooks, that those persons who are immunocompromised including those with spleen removed, persons with diabetes mellitus, cancer and alcoholism, are also at greater risk of infection.

Keywords: DIC; Streptococcus suis; fatal infection; sepsis; zoonosis.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Animals
  • Bacteremia / diagnosis
  • Bacteremia / microbiology*
  • DNA, Bacterial
  • Fatal Outcome
  • Host-Pathogen Interactions
  • Humans
  • Hungary
  • Immunocompromised Host
  • Male
  • Pork Meat / microbiology
  • RNA, Ribosomal, 16S
  • Risk Factors
  • Splenectomy / adverse effects
  • Streptococcal Infections / diagnosis*
  • Streptococcal Infections / microbiology*
  • Streptococcus suis / isolation & purification
  • Swine

Substances

  • DNA, Bacterial
  • RNA, Ribosomal, 16S