Sequencing and Characterization of Five Extensively Drug-Resistant Salmonella enterica Serotype Typhi Isolates Implicated in Human Infections from Punjab, Pakistan

Kaitlin A Tagg; Afreenish Amir; Aamer Ikram; Jessica C Chen; Justin Y Kim; Elizabeth Meservey; Yoo J Joung; Jessica L Halpin; Dhwani Batra; Molly M Leeper; Lee S Katz; Asim Saeed; Molly Freeman; Louise Francois Watkins; Muhammad Salman; Jason P Folster

doi:10.1128/MRA.01466-19

Sequencing and Characterization of Five Extensively Drug-Resistant Salmonella enterica Serotype Typhi Isolates Implicated in Human Infections from Punjab, Pakistan

Microbiol Resour Announc. 2020 Mar 26;9(13):e01466-19. doi: 10.1128/MRA.01466-19.

Authors

Kaitlin A Tagg¹, Afreenish Amir², Aamer Ikram³, Jessica C Chen⁴, Justin Y Kim^{4

5}, Elizabeth Meservey¹, Yoo J Joung^{4

5}, Jessica L Halpin⁴, Dhwani Batra⁴, Molly M Leeper⁴, Lee S Katz^{4

6}, Asim Saeed³, Molly Freeman⁴, Louise Francois Watkins⁴, Muhammad Salman³, Jason P Folster⁴

Affiliations

¹ Weems Design Studio, Inc., Suwanee, Georgia, USA.
² National Institute of Health, Islamabad, Pakistan afreenish.hassan@yahoo.com.
³ National Institute of Health, Islamabad, Pakistan.
⁴ Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
⁵ Oak Ridge Institute for Science and Education, Oak Ridge, Tennessee, USA.
⁶ Center for Food Safety, University of Georgia, Griffin, Georgia, USA.

Abstract

A large outbreak of extensively drug-resistant (XDR) Salmonella enterica serotype Typhi infections is ongoing in Pakistan, predominantly in Sindh Province. Here, we report the sequencing and characterization of five XDR Salmonella Typhi isolates from the Punjab province of Pakistan that are closely related to the outbreak strain and carry the same IncY plasmid.