Broadband and Ultrasensitive Graphene-Based Mechanical Wave Detector with Nanosecond Response Used for Biological Photoacoustic Imaging

ACS Appl Mater Interfaces. 2020 Apr 15;12(15):17268-17275. doi: 10.1021/acsami.0c02112. Epub 2020 Apr 2.

Abstract

Achieving broadband and sensitive mechanical wave detection with fast time response remains a great challenge. Here, we exploited the polarization-sensitive absorption characteristics and ultrafast photoelectric response of graphene to construct a broadband and ultrasensitive detector with a nanosecond response for mechanical wave detection. The unprecedented performance of the graphene-based detector allowed us to detect high-frequency mechanical waves over 100 MHz with a detection limit of 0.18 kPa. Moreover, we applied the detector in high-contrast photoacoustic imaging of human hairs and a mouse hindlimb to demonstrate its capability in detection of photoacoustic waves. This device could also find application in other areas such as THz detection and modulation.

Keywords: Photoacoustic detection and imaging; biological tissue imaging; graphene; mechanical waves detection; ultrafast optical sensors; ultrasensitive biosensors.

MeSH terms

  • Animals
  • Graphite / chemistry*
  • Hair / diagnostic imaging
  • Hindlimb / diagnostic imaging
  • Humans
  • Mice
  • Mice, Nude
  • Photoacoustic Techniques / methods*

Substances

  • Graphite