Motor Proteins: It Runs in the Family, but at Different Speeds

Aniruddha Mitra; Erwin J G Peterman

doi:10.1016/j.cub.2020.02.005

Motor Proteins: It Runs in the Family, but at Different Speeds

Curr Biol. 2020 Mar 23;30(6):R282-R285. doi: 10.1016/j.cub.2020.02.005.

Authors

Aniruddha Mitra¹, Erwin J G Peterman²

Affiliations

¹ Department of Physics and Astronomy, and LaserLaB Amsterdam, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
² Department of Physics and Astronomy, and LaserLaB Amsterdam, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands. Electronic address: e.j.g.peterman@vu.nl.

PMID: 32208157
DOI: 10.1016/j.cub.2020.02.005

Abstract

The velocity of intraflagellar transport among evolutionarily distant organisms differs substantially, while the transport machinery is well conserved. A new in vitro study finds that the velocity difference is encoded in the motor proteins driving transport.

Publication types

Comment

MeSH terms

Cilia / metabolism
Dyneins / metabolism
Flagella* / metabolism
Kinesins* / metabolism
Protein Transport

Substances

Dyneins
Kinesins