Membrane Remodeling: Passive Crosslinkers Drive Membrane Tubulation

Curr Biol. 2020 Mar 23;30(6):R270-R272. doi: 10.1016/j.cub.2020.01.058.

Abstract

A new study has uncovered three mechanisms of motor-independent membrane tubulation. In vitro reconstitution using a minimal set of proteins shows that the accumulation of crosslinking proteins at the membrane-microtubule interface is sufficient to drive tubulation, which is enhanced by coupling with microtubule dynamics.

Publication types

  • Comment

MeSH terms

  • Microtubules*
  • Proteins*

Substances

  • Proteins