Identification of Predictive Factors for Mechanical Complications After Adult Spinal Deformity Surgery: A Multi-Institutional Retrospective Study

Spine (Phila Pa 1976). 2020 Sep 1;45(17):1185-1192. doi: 10.1097/BRS.0000000000003500.

Abstract

Study design: A retrospective multicenter observational study.

Objective: To investigate correction surgeries that were performed in relatively aged patients in terms of mechanical complications (MCs) and their predictive factors.

Summary of background data: The risk factors associated with MCs have not yet been well examined, especially in aged populations.

Methods: We retrospectively reviewed 230 surgically treated ASD patients with an average age of 72.2 years. Twenty-eight patients with ASD caused by vertebral fractures were excluded. The minimum follow-up was 2 years. Postoperative MCs were defined as proximal junction kyphosis, distal junction kyphosis, pseudoarthrosis, rod breakage, and vertebral fractures. We divided all the ASD patients into two groups: patients with MC (the MC (+) group) and patients without MC (the MC (-) group). Radiographic parameters were evaluated before and immediately after surgery. The SRS-Schwab ASD classification and global alignment and proportion (GAP) score were also evaluated.

Results: Of the 202 patients, 91 (45.0%) had MCs. The age at surgery was significantly higher in the MC (+) group than in the MC (-) group. Regarding radiographic parameters, postoperative global tilt (GT), pre- and postoperative thoracolumbar kyphosis (TLK), and postoperative thoracic kyphosis were significantly higher in the MC (+) group than in the MC (-) group. Other parameters, such as the proposed ideal alignment target of PI-LL<10, did not significantly affect MC rates. The GAP score was high in both groups and not significantly related to a higher rate of MC. Forward stepwise logistic regression indicated that the age at surgery, postoperative GT, and preoperative TLK were significant risk factors for MCs.

Conclusion: Older age, higher postoperative GT, and higher pre and postoperative TLK can be risk factors for MCs. The GAP score was high in both groups and not significantly related to a higher rate of MC.

Level of evidence: 4.

Publication types

  • Multicenter Study
  • Observational Study

MeSH terms

  • Aged
  • Aged, 80 and over
  • Biomechanical Phenomena / physiology*
  • Female
  • Humans
  • Kyphosis / diagnostic imaging
  • Kyphosis / surgery
  • Lumbar Vertebrae / diagnostic imaging
  • Lumbar Vertebrae / surgery
  • Male
  • Middle Aged
  • Neurosurgical Procedures / adverse effects*
  • Neurosurgical Procedures / trends
  • Postoperative Complications / diagnostic imaging*
  • Postoperative Complications / etiology
  • Postoperative Complications / physiopathology*
  • Predictive Value of Tests
  • Retrospective Studies
  • Spinal Diseases / diagnostic imaging*
  • Spinal Diseases / surgery*
  • Thoracic Vertebrae / diagnostic imaging
  • Thoracic Vertebrae / surgery