Cryo-EM structure of human heptameric Pannexin 1 channel

Affiliations

• ¹ Institute of Pediatrics, Children's Hospital of Fudan University and Institutes of Biomedical Sciences, State Key Laboratory of Genetic Engineering and School of Life Sciences, Fudan University, Shanghai, 200032, China.
• ² Shanghai Ji Ai Genetics and IVF Institute, Obstetrics and Gynecology Hospital, Fudan University, Shanghai, 200011, China.
• ³ Cryo-Electron Microscopy Research Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
• ⁴ The CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
• ⁵ Institute of Neuroscience, State Key Laboratory of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, 200031, China.
• ⁶ Cryo-Electron Microscopy Research Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China. xkyu@simm.ac.cn.
• ⁷ The CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China. xkyu@simm.ac.cn.
• ⁸ Institute of Pediatrics, Children's Hospital of Fudan University and Institutes of Biomedical Sciences, State Key Laboratory of Genetic Engineering and School of Life Sciences, Fudan University, Shanghai, 200032, China. wangleiwanglei@fudan.edu.cn.
• ⁹ Zhuhai Fudan Innovation Institute, Zhuhai, 519000, Guangdong, China. wangleiwanglei@fudan.edu.cn.
• ¹⁰ Institute of Neuroscience, State Key Laboratory of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, 200031, China. shujiazhu@ion.ac.cn.