Finding sense in the context

Elife. 2020 Mar 23:9:e55960. doi: 10.7554/eLife.55960.

Authors

Kim M Keeling^{1

2}, David M Bedwell^{1

2}

Affiliations

¹ Department of Biochemistry and Molecular Genetics, University of Alabama at Birmingham, Birmingham, United States.
² Gregory Fleming James Cystic Fibrosis Research Center, University of Alabama at Birmingham, Birmingham, United States.

Abstract

Ribosomal profiling has shed new light on how ribosomes can ignore stop codons in messenger RNA.

Keywords: aminoglycoside; chromosomes; gene expression; human; readthrough; ribosome; ribosome profiling; translation.

© 2020, Keeling and Bedwell.

Publication types

Comment

MeSH terms

Aminoglycosides*
Anti-Bacterial Agents
Codon, Terminator
RNA, Messenger / genetics
Ribosomes* / genetics

Substances

Aminoglycosides
Anti-Bacterial Agents
Codon, Terminator
RNA, Messenger

Grants and funding

P30 DK072482/DK/NIDDK NIH HHS/United States