Dietary exposure assessment of sum deoxynivalenol forms, sum T-2/HT-2 toxins and zearalenone from cereal-based foods and beer

Food Chem Toxicol. 2020 May:139:111280. doi: 10.1016/j.fct.2020.111280. Epub 2020 Mar 18.

Abstract

A dietary exposure assessment to sum of deoxynivalenol (DON) forms, sum of T-2/HT-2 toxins (T2/HT2) and zearalenone (ZEA) was conducted for Czech children 4-6 years and Czech men and women 18-59 years. Retail foods (25 different commodities, n = 336) were assessed by LC-MS/MS methods. The 95th percentile chronic exposure to sum of DON forms was determined in children from 648 to 1030 ng/kg bw/day (LB/lower bound/and UB/upper bound/), in men from 362 to 923 ng/kg bw/day and in women from 272 to 490 ng/kg bw/day. The 95th percentile chronic exposure to sum T2/HT2 was determined in children from 6.5 to 31 ng/kg bw/day, in men from 1.9 to 11.2 ng/kg bw/day and in women from 2.5 to 11.5 ng/kg bw/day. The 95th percentile chronic exposure to ZEA was determined in children from 11.9 to 24.9 ng/kg bw/day, in men from 5.9 to 27.5 ng/kg bw/day and in women from 4.8 to 12.6 ng/kg bw/day. The risk linked with the mean and the 95th percentile chronic exposure (LB scenario) to the sum of DON forms, sum of T2/HT2 and ZEA is considered to be out of health concern for the selected population groups.

Keywords: Beer; Cereal-based food; Deoxynivalenol forms; Dietary exposure; T-2/HT-2 toxins; Zearalenone.

MeSH terms

  • Adolescent
  • Adult
  • Beer / analysis*
  • Child
  • Child, Preschool
  • Dietary Exposure*
  • Edible Grain / chemistry*
  • Female
  • Food Contamination / analysis
  • Humans
  • Male
  • Middle Aged
  • Mycotoxins / analysis
  • T-2 Toxin / analogs & derivatives*
  • T-2 Toxin / toxicity*
  • Trichothecenes / toxicity*
  • Young Adult
  • Zearalenone / toxicity*

Substances

  • Mycotoxins
  • Trichothecenes
  • Zearalenone
  • T-2 Toxin
  • deoxynivalenol
  • HT-2 toxin