Data on treatment of nafcillin and ampicillin antibiotics in water by sonochemistry

Diana M Montoya-Rodríguez; Yenny Ávila-Torres; Efraím A Serna-Galvis; Ricardo A Torres-Palma

doi:10.1016/j.dib.2020.105361

Data on treatment of nafcillin and ampicillin antibiotics in water by sonochemistry

Data Brief. 2020 Mar 2:29:105361. doi: 10.1016/j.dib.2020.105361. eCollection 2020 Apr.

Authors

Diana M Montoya-Rodríguez¹, Yenny Ávila-Torres², Efraím A Serna-Galvis¹, Ricardo A Torres-Palma¹

Affiliations

¹ Grupo de Investigación en Remediación Ambiental y Biocatálisis (GIRAB), Instituto de Química, Facultad de Ciencias Exactas y Naturales, Universidad de Antioquia UdeA, Calle 70 No. 52-21, Medellín, Colombia.
² Grupo de Investigación QUIBIO, Facultad de Ciencias Básicas, Universidad Santiago de Cali, Santiago de Cali, Pampalinda, Colombia.

Abstract

Ampicillin and nafcillin antibiotics were treated by high frequency ultrasound (at 375 kHz and 24.4 W). Degradations followed pseudo-first order kinetics, which constants were k: 0.0323 min^-1 for AMP and k: 0.0550 min^-1 for NAF. Accumulation of sonogenerated hydrogen peroxide and inhibition degree of sonochemical removal (IDS) in presence of a radical scavenger were also stablished. Afterwards, ultrasound was combined with UVC light (sono-photolysis), with ferrous ion (sono-Fenton), and with ferrous ion plus UVC light (sono-photo-Fenton) to degrade the antibiotics. Furthermore, treatment of the pollutants in a complex matrix and removal of antimicrobial activity (AA) were considered. The antibiotics evolution was followed by HPLC-DAD technique and the accumulation of sonogenerated H₂O₂ was measured by an iodometry-spectrophotometry methodology (77.6 and 57.3 μmol L^-1 of H₂O₂ after 30 min of sonication were accumulated in presence of AMP and NAF, respectively). IDS was analyzed through treatment of the antibiotics in presence of 2-propanol (87.1% for AMP and 56 % for NAF) and considering the hydrophobic character of pollutants (i.e., Log P values). Antimicrobial activity evolution was assessed by the Kirby-Bauer method using Staphylococcus aureus as indicator microorganism (sono-photo-Fenton process removed 100% of AA after 60 and 20 min for AMP and NAF, respectively). Finally, for degradations in the complex matrix, a simulated effluent of municipal wastewater treatment plant was utilized (sono-photo-Fenton led to degradations higher than 90 % at 60 min of treatment for both antibiotics). The data from the present work can be valuable for people researching on treatment of wastewaters containing antibiotics, application of advanced oxidation technologies and combination of sonochemical process with photochemical systems.

Keywords: Combination of processes; Matrix effect; Sonochemistry; Water treatment; β-Lactam antibiotics.