Microwave-assisted synthesis of rhodamine derivatives

Green Chem Lett Rev. 2018;11(3):237-245. doi: 10.1080/17518253.2018.1472814. Epub 2018 May 14.

Abstract

The microwave synthesis of 12 rhodamine-derived imines is described. The present work involves condensation of rhodamine hydrazide with various aromatic aldehydes in ethanol under microwave irradiation. The results obtained indicate that, unlike classical heating, microwave irradiation results in higher yields, shorter reaction time, mild reaction condition and simple work-up procedure. The structures of synthesized compounds were confirmed by 1H-NMR, 13C-NMR, FT-IR and high-resolution mass spectra data.

Keywords: Microwave irradiation; green chemistry; rhodamine-derived imines.