Microbiome and cancer immunotherapy

Curr Opin Biotechnol. 2020 Oct:65:114-117. doi: 10.1016/j.copbio.2020.02.007. Epub 2020 Mar 17.

Abstract

Immunomodulation has become a promising and growing field of cancer research. Compelling results from a variety of studies provide strong evidence for the importance of commensal bacteria on oncologic outcomes and response to antitumor immunotherapies. The gut microbiome has emerged as a new prognostic biomarker and a potential therapeutic target to enhance the efficacy of immunotherapy.

Publication types

  • Review

MeSH terms

  • Gastrointestinal Microbiome*
  • Humans
  • Immunity
  • Immunotherapy
  • Microbiota*
  • Neoplasms* / therapy