A Novel Hepe-Like Virus from Farmed Giant Freshwater Prawn Macrobrachium rosenbergii

Viruses. 2020 Mar 17;12(3):323. doi: 10.3390/v12030323.

Abstract

The family Hepeviridae includes several positive-stranded RNA viruses, which infect a wide range of mammalian species, chicken, and trout. However, few hepatitis E viruses (HEVs) have been characterized from invertebrates. In this study, a hepevirus, tentatively named Crustacea hepe-like virus 1 (CHEV1), from the economically important crustacean, the giant freshwater prawn Macrobrachium rosenbergii, was characterized. The complete genome consisted of 7750 nucleotides and had a similar structure to known hepatitis E virus genomes. Phylogenetic analyses suggested it might be a novel hepe-like virus within the family Hepeviridae. To our knowledge, this is the first hepe-like virus characterized from crustaceans.

Keywords: Crustacea hepe-like virus 1; Hepeviridae; Macrobrachium rosenbergii.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animal Diseases / virology
  • Animals
  • Fresh Water
  • Genome, Viral
  • Genomics / methods
  • Hepevirus / classification*
  • Hepevirus / genetics*
  • Hepevirus / isolation & purification
  • Open Reading Frames
  • Palaemonidae / virology*
  • Phylogeny
  • RNA, Viral

Substances

  • RNA, Viral