[Fracture prevention in metastatic prostate cancer]

Ned Tijdschr Geneeskd. 2020 Feb 18:164:D4016.
[Article in Dutch]

Abstract

Patients with metastatic prostate cancer are living longer than they used to, thanks to a wider range of therapeutic options. This means that an increasing number of men will receive long-term treatment with anti-hormonal therapy - androgen-deprivation therapy (ADT) - and the risk of side effects from this therapy is increasing. A relevant decrease in bone density is increasingly seen in patients receiving ADT, which means that a disproportionate increase in risk of fractures is seen in aging patients. Urologists are confronted with these patients in clinical practice. The question is how urologist-care for these patients is organised in the Netherlands. A survey among urologists in the Netherlands revealed that there is great diversity in how they think and act, and that there is a need for national guidelines and additional training on this subject.

MeSH terms

  • Aged
  • Androgen Antagonists / adverse effects*
  • Antineoplastic Agents, Hormonal / adverse effects*
  • Bone Density / drug effects
  • Fractures, Bone / chemically induced
  • Fractures, Bone / prevention & control*
  • Hormone Replacement Therapy / adverse effects*
  • Humans
  • Male
  • Middle Aged
  • Netherlands
  • Prostatic Neoplasms / drug therapy*

Substances

  • Androgen Antagonists
  • Antineoplastic Agents, Hormonal