Adjuvant Therapy With Mushroom Polysaccharides for Diabetic Complications

Xue Jiang; Weiqi Meng; Lanzhou Li; Zhaoli Meng; Di Wang

doi:10.3389/fphar.2020.00168

Adjuvant Therapy With Mushroom Polysaccharides for Diabetic Complications

Front Pharmacol. 2020 Feb 28:11:168. doi: 10.3389/fphar.2020.00168. eCollection 2020.

Authors

Xue Jiang^{1

2}, Weiqi Meng², Lanzhou Li², Zhaoli Meng¹, Di Wang²

Affiliations

¹ Department of Translational Medicine Research Institute, First Hospital, Jilin University, Changchun, China.
² School of Life Sciences, Jilin University, Changchun, China.

Abstract

Background: Diabetic complications seriously endanger the health of most diabetic patients around the world. Most chemical hypoglycemic agents have adverse effects and are unable to improve the progression of diabetic complications. In recent years, a number of medicinal herbs have become increasingly popular for the treatment of diabetic complications due to their relative safety. Polysaccharides extracted from medicinal herbs with multiple pharmacological activities and low toxicity have been reported to be useful in the treatment of diabetic complications.

Methods: Primary studies with keywords including polysaccharide and diabetic complications were retrieved from the Web of Science and NCBI databases and were read and analyzed.

Results: Mushroom polysaccharides were proven to have positive effects on diabetic complications.

Conclusions: We studied the effects of mushroom polysaccharides on hyperglycemia and as adjuvant therapies for diabetic complications and summarized the applications and limitations of mushroom polysaccharides to better understand their application for the treatment of diabetic complications.

Keywords: diabetes; diabetic complications; mushroom; polysaccharides; structure.

Publication types

Review