Heavy charged particles for gastrointestinal cancers

Yuka Isozaki; Hirotoshi Takiyama; Tapesh Bhattacharyya; Daniel Ebner; Goro Kasuya; Hirokazu Makishima; Hiroshi Tsuji; Tadashi Kamada; Shigeru Yamada

doi:10.21037/jgo.2019.03.14

Heavy charged particles for gastrointestinal cancers

J Gastrointest Oncol. 2020 Feb;11(1):203-211. doi: 10.21037/jgo.2019.03.14.

Authors

Yuka Isozaki¹, Hirotoshi Takiyama¹, Tapesh Bhattacharyya¹, Daniel Ebner¹, Goro Kasuya¹, Hirokazu Makishima¹, Hiroshi Tsuji¹, Tadashi Kamada¹, Shigeru Yamada¹

Affiliation

¹ Department of Radiation Oncology, Hospital of the National Institute of Radiological Science, National Institutes for Quantum and Radiological Science and Technology, Chiba, Japan.

Abstract

Carbon ion beams constitute the primary delivery method of heavy ion radiotherapy. It offers improved dose distribution, and enables concentration of dose within target volumes with minimal extraneous exposure of normal tissue, while delivering superior biological effect in comparison with photon and proton technologies. Here, we review the application of this technology to various gastrointestinal cancers.

Keywords: Gastrointestinal cancer; carbon-ion radiotherapy (CIRT); heavy ion radiotherapy.

Publication types

Review