Effect of Axial Length Adjustment Methods on Intraocular Lens Power Calculation in Highly Myopic Eyes

Am J Ophthalmol. 2020 Jun:214:110-118. doi: 10.1016/j.ajo.2020.02.023. Epub 2020 Mar 12.

Abstract

Purpose: To evaluate the performance of Holladay 1 and SRK/T formulas with the axial length (AL) adjustment methods including the linear and nonlinear versions of Wang-Koch AL adjustment methods and Cooke-modified AL (CMAL); and to determine whether the CMAL should be extended to the latest Barrett Universal II, Ladas Super formula (LSF), and Emmetropia Verifying Optical formulas in highly myopic eyes.

Design: Retrospective, consecutive case-series study.

Methods: A total of 164 eyes of 164 patients with AL ≥26.0 mm were included and divided into 2 groups: AL <28.0 mm (Group 1) and AL ≥28.0 mm (Group 2). The average arithmetic spherical equivalent prediction error (PE), mean absolute PE, median absolute error (MedAE), and the percentage of eyes within ±0.25 diopter (D), ±0.50 D, and ±1.0 D of PE were determined.

Results: The Holladay 1 formulas showed the smallest MedAE when combined with the first linear or nonlinear version of Wang-Koch AL adjustment methods, both in total and in subgroups. The SRK/T formula displayed the highest prediction accuracy in combination with the first linear version of Wang-Koch adjustment method in total and subgroups. The CMAL reduced the absolute PE of LSF in total (P = .003) and in Group 1 (P = .017).

Conclusions: The Holladay 1 and SRK/T formulas combined with specific AL adjustment methods had accuracy similar to the fourth-generation formulas for highly myopic eyes. Moreover, the CMAL can improve the accuracy of the LSF for highly myopic eyes.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Axial Length, Eye / pathology*
  • Biometry / methods*
  • Cataract / pathology
  • Female
  • Humans
  • Lens Implantation, Intraocular*
  • Lenses, Intraocular*
  • Male
  • Middle Aged
  • Myopia, Degenerative / pathology*
  • Optics and Photonics
  • Phacoemulsification*
  • Retrospective Studies
  • Visual Acuity