The Structure of ASFV Advances the Fight against the Disease

Yuejiao Xian; Chuan Xiao

doi:10.1016/j.tibs.2020.01.007

The Structure of ASFV Advances the Fight against the Disease

Trends Biochem Sci. 2020 Apr;45(4):276-278. doi: 10.1016/j.tibs.2020.01.007. Epub 2020 Feb 17.

Authors

Yuejiao Xian¹, Chuan Xiao²

Affiliations

¹ Department of Chemistry and Biochemistry, University of Texas at El Paso, El Paso, TX 79968, USA.
² Department of Chemistry and Biochemistry, University of Texas at El Paso, El Paso, TX 79968, USA. Electronic address: cxiao@utep.edu.

Abstract

African swine fever virus (ASFV) is the causative pathogen of the recent African swine fever epidemic, with devastating impacts on economy. A recent study by Wang et al. reveals the multilayer structural details of ASFV at near-atomic resolution, which provides interesting insights about giant virus assembly and paves the way for vaccine development.

Publication types

Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Comment

MeSH terms

African Swine Fever Virus*
African Swine Fever*
Animals
Swine
Viral Proteins
Virus Assembly

Substances

Viral Proteins

Grants and funding

R01 GM129525/GM/NIGMS NIH HHS/United States