Uterine-conserving approach in ruptured intramyometrial ectopic pregnancy

Horm Mol Biol Clin Investig. 2020 Mar 13;41(2). doi: 10.1515/hmbci-2020-0001.

Abstract

Intramyometrial ectopic pregnancy (IMEP) is a rare form of ectopic pregnancy. It is defined as a conceptus implanted within the myometrium and is completely surrounded by myometrium with clear separation from both the uterine cavity and tubes. IMEP possesses not only diagnostic but also therapeutic challenge. The majority of reported cases were managed by hysterectomy. Early management of unruptured IMEP using methotrexate may help to preserve fertility. We, for the first time, report a case of ruptured IMEP managed successfully using suction and curettage followed by Bakri balloon tamponade and avoiding hysterectomy. Post-procedure, the patient received two doses of intramuscular methotrexate 50 mg/m2 due to plateauing serial beta human chorionic gonadotropin (β-hCG) levels and subsequently achieved undetectable level 10 weeks post-methotrexate. She also had complete resolution of the ectopic intramyometrial mass.

Keywords: ectopic pregnancy; intramyometrial ectopic; methotrexate; ruptured ectopic.

Publication types

  • Case Reports

MeSH terms

  • Abortifacient Agents, Nonsteroidal / therapeutic use
  • Adult
  • Chorionic Gonadotropin, beta Subunit, Human / blood
  • Female
  • Humans
  • Methotrexate / therapeutic use
  • Myometrium* / diagnostic imaging
  • Organ Sparing Treatments / methods*
  • Pregnancy
  • Pregnancy, Ectopic / blood
  • Pregnancy, Ectopic / diagnostic imaging
  • Pregnancy, Ectopic / surgery*
  • Rupture, Spontaneous
  • Uterine Balloon Tamponade*
  • Uterine Hemorrhage / etiology
  • Uterine Hemorrhage / therapy
  • Uterine Rupture / etiology
  • Uterine Rupture / therapy*
  • Vacuum Curettage*

Substances

  • Abortifacient Agents, Nonsteroidal
  • Chorionic Gonadotropin, beta Subunit, Human
  • Methotrexate