The Use of Natural Materials in Film Coating for Controlled Oral Drug Release

Curr Med Chem. 2021;28(9):1829-1840. doi: 10.2174/0929867327666200312113547.

Abstract

Background: Although synthetic materials have been used in film coating processes for drug delivery for many years, substantial studies on natural materials have also been conducted because of their biodegradable and unique properties.

Methods: Because of the ability to form and modify films for controlled oral drug delivery, increasing attention has been shown to these materials in the design of film coating systems in recent research.

Results: This review aims to provide an overview of natural materials focusing on film coating for oral delivery, specifically in terms of their classification and their combinations in film coating formulations for adjusting the desired properties for controlled drug delivery.

Conclusions: Discussing natural materials and their potential applications in film coating would benefit the optimization of processes and strategies for future utilization.

Keywords: Controlled drug delivery; drug administration; film formation; film coating formulation; natural coating materials; oral drug delivery.

Publication types

  • Review

MeSH terms

  • Drug Carriers*
  • Drug Compounding
  • Drug Delivery Systems*
  • Drug Liberation
  • Humans

Substances

  • Drug Carriers