Relationship Between Ginsenoside Rg3 and Metabolic Syndrome

Hyunji Lee; Gyeyeong Kong; Quangdon Tran; Chaeyeong Kim; Jisoo Park; Jongsun Park

doi:10.3389/fphar.2020.00130

Relationship Between Ginsenoside Rg3 and Metabolic Syndrome

Front Pharmacol. 2020 Feb 25:11:130. doi: 10.3389/fphar.2020.00130. eCollection 2020.

Authors

Hyunji Lee^{1

2}, Gyeyeong Kong^{1

2}, Quangdon Tran^{1

2}, Chaeyeong Kim^{1

2}, Jisoo Park^{1

2

3}, Jongsun Park^{1

2}

Affiliations

¹ Department of Pharmacology, College of Medicine, Chungnam National University, Daejeon, South Korea.
² Department of Medical Science, Metabolic Syndrome and Cell Signaling Laboratory, Institute for Cancer Research, College of Medicine, Chungnam National University, Daejeon, South Korea.
³ Department of Life Science, Hyehwa Liberal Arts College, Daejeon University, Daejeon, South Korea.

Abstract

Metabolic syndrome is an important public health issue and is associated with a more affluent lifestyle. Many studies of metabolic syndrome have been reported, but its pathogenesis remains unclear and there is no effective treatment. The ability of natural compounds to ameliorate metabolic syndrome is currently under investigation. Unlike synthetic chemicals, such natural products have proven utility in various fields. Recently, ginsenoside extracted from ginseng and ginseng root are representative examples. For example, ginseng is used in dietary supplements and cosmetics. In addition, various studies have reported the effects of ginsenoside on metabolic syndromes such as obesity, diabetes, and hypertension. In this review, we describe the potential of ginsenoside Rg3, a component of ginseng, in the treatment of metabolic syndrome.

Keywords: NAFLD; Rg3; ginsenoside; metabolic syndrome; obesity.

Publication types

Review