Diagnosis and Treatment of Trauma-Induced Coagulopathy by Viscoelastography

Semin Thromb Hemost. 2020 Mar;46(2):134-146. doi: 10.1055/s-0040-1702171. Epub 2020 Mar 11.

Abstract

This article explores the application of viscoelastic tests (VETs) in trauma-induced coagulopathy and trauma resuscitation. We describe the advantages of VETs over conventional coagulation tests in the trauma setting and refer to previous disciplines in which VET use has reduced blood product utilization, guided prohemostatic agents, and improved clinical outcomes such as the mortality of critically bleeding patients. We describe different VETs and provide guidance for blood component therapy and prohemostatic therapy based on specific VET parameters. Because the two most commonly used VET systems, rotational thromboelastometry and thromboelastography, use different activators and have different terminologies, this practical narrative review will directly compare and contrast these two VETs to help the clinician easily interpret either and use the interpretation to determine hemostatic integrity in the bleeding trauma patient. Finally, we anticipate the future of new viscoelastic technologies that can be used in this setting.

Publication types

  • Review

MeSH terms

  • Blood Coagulation Disorders / diagnosis*
  • Blood Coagulation Disorders / therapy*
  • Humans
  • Thrombelastography / methods*
  • Wounds and Injuries / blood*
  • Wounds and Injuries / complications